Bldg.5(School of Pharmacy)
[Chemical Biology]
Thursday, March 26, AM
Chair: FUKASE, Koichi
(10:30-11:30)
* 10:20-10:30: interval for laptop PC connection.(1J7-10)
1J7-10 CSJ Award for Creative Works
Development of antibacterial Agents using Chemical Biology Techniques (Grad. Sch. Life Sci., Tohoku Univ.) º ARIMOTO, Hirokazu
Chair: ITTO, Kaori
(11:40-12:20)
* 11:30-11:40: interval for laptop PC connection.(1J7-17, 1J7-18, 1J7-19, 1J7-20)
1J7-17
Application of dual-probe photoaffinity labeling toward exploration of carbohydrate binding proteins (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º OZAWA, Shimpei; SAKURAI, Kaori; ISHIKAWA, Hideaki
1J7-18
Iron-catalyzed tyrosine-specific chemical modification of proteins with luminol derivatives (Chem. Res. Lab., Tokyo Tech) º NAKAMURA, Kosuke; SATO, Shinichi; NAKAMURA, Hiroyuki
1J7-19
Regulation of protein functions with sterically-bulky synthetic protection groups (Fac. Eng., The Univ. of Tokyo; RCAST, The Univ. of Tokyo) º KATADA, Sumika; YAMAGUCHI, Satoshi; SHIOTA, Hidefumi; OKAMOTO, Akimitsu
1J7-20
Paramagnetic NMR study of proteins with DOTA-M8 ligands (RIKEN Synthetic Organic Chemistry Laboratry; RIKEN CSRS; RIKEN QBiC; Grad. Sch. Sci. Eng., Tokyo Metropolitan Univ.) º HIKONE, Yuya; INOMATA, Kohsuke; KAMOSHIDA, Hajime; IINUMA, Junya; HIRAI, Go; SODEOKA, Mikiko; MISHIMA, Masaki; ITO, Yutaka
Thursday, March 26, PM
Chair: YOSHIMURA, Hideaki
(13:30-14:30)
* 13:20-13:30: interval for laptop PC connection.(1J7-28, 1J7-29, 1J7-30, 1J7-31, 1J7-32)
1J7-28
A labeling method for proteins in living cells using biotin ligase fused to fluorescent protein (Grad. Sch. Fac. CSSE., KIT) NISHI, Sairi; YAMAMOTO, Chihiro; º SUEDA, Shinji
1J7-29
Development of a highly sensitive screening method for CXCR4 ligands based on time-resolved FRET (IBB, Tokyo Med. and Dental Univ.) º TAKETOMI, Shohei; NOMURA, Wataru; TAMAMURA, Hirokazu
1J7-30
Development of pH-activatable Fluorescent Probe with Red-shifted Emission and Hydroxyapatite-binding ability (Grad. Sch. Eng., Osaka Univ.) º MAEDA, Hiroki; KOWADA, Toshiyuki; KIKUCHI, Kazuya
1J7-31
Protein labeling using LDSP chemistry (1) Expansion of target proteins under living cell conditions (Grad. Sch. Eng., Kyoto Univ.; CREST, JST) º NISHIKAWA, Yuki; MASUDA, Marie; MATSUO, Kazuya; HAMACHI, Itaru
1J7-32*
Protein labeling using LDSP chemistry: Reactivity tuning for rapid labeling (Grad. Sch. Eng., Kyoto Univ.; CREST, JST) º MASUDA, Marie; MATSUO, Kazuya; NISHIKAWA, Yuki; HAMACHI, Itaru
Chair: KIGOSHI, Hideo
(14:40-15:40)
* 14:30-14:40: interval for laptop PC connection.(1J7-35)
1J7-35 CSJ Award for Creative Works
Studies on Syntheses of Certain Carbohydrates and Antibiotics and Development of Photoactivatable Biofunctional Molecules (Fac. Sci. Tech., Keio Univ.) º TOSHIMA, Kazunobu
Chair: KONDO, Teruyuki
(15:50-16:50)
* 15:40-15:50: interval for laptop PC connection.(1J7-42, 1J7-43, 1J7-44, 1J7-46)
1J7-42
Challenges for highly sensitive NMR molecular sensor (1): Exploration of molecular structure with long hyperpolarization lifetime (Grad. Sch. Eng., The Univ. of Tokyo; CREST, JST) º IMAKURA, Yuki; NONAKA, Hiroshi; SANDO, Shinsuke
1J7-43
Challenges for highly sensitive NMR molecular sensor (2) : Hyperpolarized NMR molecular seonsor for long-term analysis of biological events (Grad. Sch. Eng., Kyushu Univ.; Grad. Sch. Eng., The Univ. of Tokyo; CREST, JST) º HIRANO, Masashi; NONAKA, Hiroshi; NISHIHARA, Tatsuya; SANDO, Shinsuke
1J7-44*
Challenges for highly sensitive NMR molecular sensor (3): Proposal of versatile strategy for designing various hyperpolarized NMR sensors. (Grad. Sch. Eng., Kyushu Univ.; Grad. Sch. Eng., The Univ. of Tokyo; CREST, JST) º NISHIHARA, Tatsuya; NONAKA, Hiroshi; KAMEYAMA, Yutaka; SANDO, Shinsuke
1J7-46*
Chemical Biology of Neuronal Synapses (1) Chemical labeling of GABA receptors, major inhibitory neurotransmitter receptors. (Grad. Sch. Eng., Kyoto Univ.; CREST, JST) º YAMAURA, Kei; KIYONAKA, Shigeki; HAMACHI, Itaru
Chair: SANDO, Shinsuke
(17:00-18:00)
* 16:50-17:00: interval for laptop PC connection.(1J7-49, 1J7-51, 1J7-52, 1J7-53, 1J7-54)
1J7-49*
A novel conditional protein labeling method(1):Zinc ion responsive focused proteome analysis in live cell (Grad. Sch. Eng., Kyoto Univ.; CREST, JST) º MIKI, Takayuki; AWA, Masashi; KIYONAKA, Shigeki; HAMACHI, Itaru
1J7-51
A novel conditional protein labeling method(2):Tuning of the affinity and reactivity for Zinc ion (Sch. Eng., Kyoto Univ.; Grad. Sch. Eng., Kyoto Univ.; CREST, JST) º RI, Shin; MIKI, Takayuki; AWA, Masashi; KIYONAKA, Shigeki; HAMACHI, Itaru
1J7-52
An efficient two-photon induced fluorescent naphthalene derivative sensitive to mitochondrial membrane potential (Fac. Sci., Yamaguchi Univ.) º MORITOMO, Hiroki; FUJIKI, Shohei; SAITO, Takako; MOCHIDA, Shuhei; TOMINAGA, Makoto; SUGIHARA, Hiroyuki; SUZUKI, Yasutaka; TANI, Seiji; KAWAMATA, Jun
1J7-53
Synthesis and Characterization of New Asymmetric Cyanine Dyes for DNA Stain (Grad. Sch. Sci., Nagoya Univ.; WPI-ITbM, Nagoya Univ.) º UNO, Kakishi; ITO, Hideto; SASAKI, Taeko; SATO, Yoshikatsu; SASAKI, Narie; HIGASHIYAMA, Tetsuya; ITAMI, Kenichiro
1J7-54
Synthesis of Exciton-Controlled Hybridization-Sensitive Fluorescent RNA probes for Monitoring of Active RNA states (Grad. Sch. Eng., The Univ. of Tokyo; RCAST, The Univ. of Tokyo) º GUO, Lihao; OKAMOTO, Akimitsu
Friday, March 27, PM
Chair: HAGIHARA, Shinya
(12:40-13:40)
* 12:30-12:40: interval for laptop PC connection.(2J7-23, 2J7-24, 2J7-25, 2J7-26, 2J7-27, 2J7-28)
2J7-23
Photo-responsive cell tablet for single-cell manipulation (Fac. Eng., The Univ. of Tokyo; RCAST, The Univ. of Tokyo) º TAKAGI, Risa; YAMAGUCHI, Satoshi; SAKAKIHARA, Shouichi; TABATA, Kazuhito; IINO, Ryota; NOJI, Hiroyuki; OKAMOTO, Akimitsu
2J7-24
Studies on Transport of Oligo dT to Cell Nucleus (Grad. Sch. Eng., The Univ. of Tokyo; RCAST, The Univ. of Tokyo) º KITAGAWA, Mai; OKAMOTO, Akimitsu
2J7-25
Development of the method to detect 5-hydroxymethylcytosine by sequencing and oxidation (RCAST, The Univ. of Tokyo; Grad. Sch. Eng., The Univ. of Tokyo) º KOHYAMA, Kenta; HAYASHI, Gosuke; OKAMOTO, Akimitsu
2J7-26
Genetic Response upon Selective Removal of Endogenous CO in the Blood of Mice (Fac. Sci. Eng., Doshisha Univ.) º MINEGISHI, Saika; YUMURA, Aki; KITAGISHI, Hiroaki; NEGI, Shigeru; SUGIURA, Yukio; KANO, Koji
2J7-27
Utilizing mesoporous silica nanoparticles for optical methods to remotely control cellular functions (Grad. Sch. Eng., Kyoto Univ.) º NAKAMURA, Takuma; ITO, Takeo; TANABE, Kazuhito
2J7-28
Synthetic genetic switches for directed differentiation of human pluripotent stem cells (Grad. Sch. Sci., Kyoto Univ.) º TANIGUCHI, Junichi; SADOI, Tatsuya; NAMASIVAYAM, Ganesh Pandian; SATO, Shinsuke; BANDO, Toshikazu; SUGIYAMA, Hiroshi
Chair: KITA, Masaki
(13:50-14:50)
* 13:40-13:50: interval for laptop PC connection.(2J7-30, 2J7-31, 2J7-32, 2J7-33, 2J7-34, 2J7-35)
2J7-30
Development of calixarene-based host molecules capable of binding histone tail (Fac. Sci., Hiroshima Univ.) º KAJIKI, Yasunori; TOCHIO, Naoya; UEWAKI, Jun-ichi; TATE, Shin-ichi; HAINO, Takeharu
2J7-31
Therapeutic in vivo synthetic chemistry based on unusual reactivity of propargylic esters (RIKEN Biofunctional Synthetic Chemistry) º VONG, Kenward; TANAKA, Katsunori
2J7-32
Synthesis and properties of hydrogels cross-linked with mechanical stress-responsive bonds (Grad. Sch. Eng., The Univ. of Tokyo; RCAST, The Univ. of Tokyo) º HIGASHI, Kotaro; YAMAGUCHI, Satoshi; OKAMOTO, Akimitsu
2J7-33
Micro-patterning of plasma membrane fragments on photo-responsive surfaces (RCAST, The Univ. of Tokyo; Fac. Eng., The Univ. of Tokyo) º MISAWA, Ryuji; YAMAGUCHI, Satoshi; YAMAHIRA, Shinya; NAGAMUNE, Teruyuki; OKAMOTO, Akimitsu
2J7-34
Structure-activity Relationship Study of Small-molecule Modulator of Mammalian Circadian Clock (Grad. Sch. Sci., Nagoya Univ.; WPI-ITbM, Nagoya Univ.) º OSHIMA, Tsuyoshi; YAMANAKA, Iori; MUTO, Kei; KAWAMURA, Rika; YAMAGUCHI, Junichiro; OHKAWA-NISHIWAKI, Taeko; HIROTA, Tsuyoshi; KAY, Steve A.; YOSHIMURA, Takashi; ITAMI, Kenichiro
2J7-35
Synthesis of silylated phenylalanine derivatives and radiobromine labeling via silicon-bromine exchange reaction. (Grad. Sch. Sci. Tech., Gunma Univ.) º WATANABE, Saki; WATANABE, Shigeki; YAMADA, Keiichi; OKU, Hiroyuki; MORIGUCHI, Tomohisa; ISHIOKA, Noriko; SHINOZUKA, Kazuo
Chair: TAKAOKA, Yosuke
(15:00-16:00)
* 14:50-15:00: interval for laptop PC connection.(2J7-37, 2J7-39, 2J7-41)
2J7-37*
Development of New Inducible Protein Translocation System Based on Self-Localizing Ligands and Engineered Proteins (Nagaoka Univ. of Tech. Department of Bioengineering) OKI, Choji; º NAKAMURA, Akinobu; ISHIDA, Manabu; ISHIKAWA, Eisuke; KUWATA, Keiko; HAMACHI, Itaru; TSUKIJI, Shinya
2J7-39*
Intracellular light-triggered CO gas signaling with supramolecular proteins (Grad. Sch. Biosci. Biotech., Tokyo Tech) º FUJITA, Kenta; SHO, Takeya; OZEKI, Syuichi; ABE, Satoshi; UENO, Takafumi
2J7-41*
ATP-binding Molecular Glue for Control of Enzymatic Activity (Grad. Sch. Eng., The Univ. of Tokyo) º OKURO, Kou; SASAKI, Mizuki; AIDA, Takuzo
Chair: TSUKIJI, Shinya
(16:10-17:10)
* 16:00-16:10: interval for laptop PC connection.(2J7-44, 2J7-45, 2J7-46, 2J7-47, 2J7-48, 2J7-49)
2J7-44
Analysis of the interaction between glaziovianin A and microtubule (Grad. Sch. Pure Appl. Sci., Univ. of Tsukuba; Grad. Sch. Life and Env. Sci., Univ. of Tsukuba; Grad. Sch. Nat. Sci. Technol., Okayama Univ.) º SHIODA, Shuuya; CHINEN, Takumi; USUI, Takeo; HAYAKAWA, Ichiro; KIGOSHI, Hideo
2J7-45
Development of a high sensitive PKC ligand binding assay method (IBB, Tokyo Med. and Dental Univ.) OHASHI, Nami; º HIGASHI, Takayoshi; NOMURA, Wataru; TAMAMURA, Hirokazu
2J7-46
Development of the FRET-type ligand binding assay using PKC as a model protein (IBB, Tokyo Med. and Dental Univ.) º OHASHI, Nami; NOMURA, Wataru; TAMAMURA, Hirokazu
2J7-47
Development of useful molecular probe to reveal the mechanism of stomatal opening caused by phytotoxin coronatine (Grad. Sch. Sci., Tohoku Univ.) º IWASHITA, Toshiki; TASHITA, Ryou; TAKAOKA, Yousuke; SUZUKI, Takeshi; EGOSI, Syusuke; KASHIMOTO, Naoki; ISHIMARU, Yasuhiro; UEDA, Minoru
2J7-48
The importance of the sugar moiety of jasmonic acid glucoside as the leaf-closing factor (Grad. Sch. Sci., Tohoku Univ.) º NUKADZUKA, Yuuki; YANG, Ganqiang; ISHIMARU, Yasuhiro; TAMURA, Satoru; MANABE, Yoshiyuki; UEDA, Minoru
2J7-49
Development of a photoaffinity probe based on an anticancer saponin OSW-1 (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º YAMADA, Rika; SAKURAI, Kaori
Saturday, March 28, AM
Chair: YAMAKOSHI, Hiroyuki
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(3J7-01, 3J7-03, 3J7-04, 3J7-05, 3J7-06)
3J7-01*
Protein-responsive nano probe (1): Mechanism of internalization and intracellular protein imaging (Grad. Sch. Eng., Kyoto Univ.) º YOSHII, Tatsuyuki; MIZUSAWA, Keigo; TAKAOKA, Yousuke; HAMACHI, Itaru
3J7-03
Protein-responsive nanoprobe (2): Intracellular imaging of Heat Shock Protein 90 (HSP90) (Sch. Eng., Kyoto Univ.) º IKEDA, Ryosuke; YOSHII, Tatsuyuki; TAKAOKA, Yousuke; HAMACHI, Itaru
3J7-04
Study on the aplyronine A binding sites to tubulin by using photoaffinity fluorescent probes (Grad. Sch. Pure Appl. Sci., Univ. of Tsukuba) º TSUCHIYA, Kota; YAMAGISHI, Kota; HIRAYAMA, Yuichiro; SEGUCHI, Yu; KITA, Masaki; KIGOSHI, Hideo
3J7-05
Evaluation of the Binding Site of Aplyronine A on Tubulin by Genetic Approach (Grad. Sch. Pure Appl. Sci., Univ. of Tsukuba; Grad. Sch. Life and Env. Sci., Univ. of Tsukuba) º YAMAGISHI, Kota; TSUCHIYA, Kota; CHINEN, Takumi; USUI, Takeo; KITA, Masaki; KIGOSHI, Hideo
3J7-06
In vivo production of eight-membered heterocycles from acrolein and transformation to 3-formyl-3,4-dehydropiperidine (FDP) as the oxidative stress marker (RIKEN Biofunctional Synthetic Chemistry Laboratory; Grad. Sch. Sci., Osaka Univ.; Kazan Univ. A. Butlerov Institute of Chemistry; PRESTO, JST) º TAKAMATU, Masayuki; FUKASE, Koichi; TANAKA, Katsunori
Chair: TAKAOKA, Yosuke
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(3J7-08, 3J7-09, 3J7-10, 3J7-11, 3J7-12, 3J7-13)
3J7-08
A natural compound yoshinone A that regulates fat metabolism (Fac. Sci., Kanagawa Univ.) º KAWAZOE, Yoshinori; UEMURA, Daisuke; SUENAGA, Kiyotake; OHNO, Osamu; IWASAKI, Arihiro
3J7-09
Synthesis of grayanotoxin probes to investigate the receptor responsible for sneezing (Fac. Sci. Tech., Keio Univ.) º UBUKATA, Yusuke; ITO, Taku; AKIYOSHI, Yuma; INOUE, Daiki; NAKATA, Masaya; SAIKAWA, Yoko
3J7-10
Inhibition of Aβ aggregation utilizing cyclo-KLVFF peptide (Grad. Sch. Pharm., The Univ. of Tokyo) º KINO, Ryuto; ARAI, Tadamasa; SOHMA, Youhei; KANAI, Motomu
3J7-11
One-pot fluorescence labelling of live cell surface by 6π-azaelectrocyclization (RIKEN Biofunctional Synthetic Chemistry Laboratory; Kazan Univ. A. Butlerov Institute of Chemistry; JST-PRESTO) º OGURA, Akihiro; TANAKA, Katsunori
3J7-12
Affinity measurement of vancomycin dimer with Staphylococcus aureus PBP2 using surface plasmon resonance (Grad. Sch. Life Sci., Tohoku Univ.) º HATAKEYAMA, Arisa; ITTO, Kaori; YUHARA, Yosie; ARIMOTO, Hirokazu
3J7-13
STD-NMR study on interaction of vancomycin dimer and S. aureus PBP2 (Grad. Sch. Life Sci., Tohoku Univ.) º ITTO, Kaori; SAKAKURA, Masayoshi; GAMO, Keizo; YUHARA, Yoshie; TAKAHASHI, Hideo; ARIMOTO, Hirokazu
Chair: TANAKA, Katsunori
(11:20-12:20)
* 11:10-11:20: interval for laptop PC connection.(3J7-15, 3J7-17, 3J7-19)
3J7-15*
Live cell imaging of small molecules utilizing alkyne-tag Raman imaging (ERATO, JST; RIKEN; CREST, JST; Grad. Sch. Eng., Osaka Univ.) º YAMAKOSHI, Hiroyuki; DODO, Kosuke; PALONPON, Almar; ANDO, Jun; OKADA, Masaya; KAWATA, Satoshi; FUJITA, Katsumasa; SODEOKA, Mikiko
3J7-17*
Construction of a library of asymmetric Si-rhodamine fluorophores based on an efficient synthesis of 4,4’-methylenebisaniline derivatives (Grad. Sch. Pharm., The Univ. of Tokyo; Grad. Sch. Med., The Univ. of Tokyo; OCDD, The Univ. of Tokyo; CREST, JST; JST Basic Research Program) º KAGAMI, Yu; HANAOKA, Kenjiro; NAGANO, Tetsuo; URANO, Yasuteru
3J7-19*
Development of the new firefly luciferin analog aiming at detection of a free radical in the living body (Grad. Sch. Sci. Tech., Keio Univ.) º IOKA, Shuji; SAITOH, Tsuyoshi; IWANO, Satoshi; MAKI, Shojiro; NIWA, Haruki; NISHIYAMA, Shigeru; IMOTO, Masaya