Bldg.5(School of Pharmacy)
[Biofunctional Chemistry ; Biotechnology]
Thursday, March 26, AM
Nucleic Acid
Chair: SEIO, Kohji
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(1J6-01, 1J6-03, 1J6-05, 1J6-06)
1J6-01*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (10): Translation suppression mediated by triplex formed by 2-aminopyridine-modified PNA and hairpin RNA (FIBER, Konan Univ.; State University of New York at Binghamton) º ENDOH, Tamaki; ROZNERS, Eriks; HNEDZKO, Dziyana; SUGIMOTO, Naoki
1J6-03*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (11): Role of compensatory base pair variation in stem regions of FMN riboswitch aptamer on its gene regulation (FIBER, Konan Univ.) º RODE, Ambadas; ENDOH, Tamaki; SUGIMOTO, Naoki
1J6-05
Creating Hypoxia Specific Oligonucleotide Therapeutics System with Intracellular Environment Responsive Peptide Ribonucleic Acids (PRNAs) (IMRAM, Tohoku Univ.) º UEMATSU, Ryohei; ASAI, Mitsuo; ARAKI, Yasuyuki; SAKAMOTO, Seiji; YAMAYOSHI, Asako; MURAKAMI, Akira; ISHIBASHI, Satoru; YOKOTA, Takanori; NAKASE, Ikuhiko; TAKAI, Madoka; WADA, Takehiko
1J6-06
Effects of Arginine Residues Introduced into Peptide Ribonucleic Acids (PRNA) upon Their Cellular Uptake Ability (IMRAM, Tohoku Univ.) º SUGAI, Hiroka; NAKASE, Ikuhiko; NISHIO, Akihiro; SAKAMOTO, Seiji; ARAKI, Yasuyuki; INOUE, Yoshihisa; TAKAI, Madoka; WADA, Takehiko
Chair: TATEISHI, Hisae
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(1J6-08, 1J6-09, 1J6-11, 1J6-12, 1J6-13)
1J6-08
Development of a methodology for the regulation of gene expression by using PNA with the crosslinking ability (IMRAM, Tohoku Univ.) º AKISAWA, Takuya; NAGATSUGI, Fumi
1J6-09*
Analysis of inteactions between phosphorothioate nucleic acids and cationic articificial peptides (Fac. Pharm. Sci., Tokyo Univ. of Sci.; JST-CREST) º MAEDA, Yusuke; NUKAGA, Youhei; IWATA, Rintaro; WADA, Takeshi
1J6-11
Creation of Protease- Activable Peptide Nucleic Acid (IMRAM, Tohoku Univ.) º SAKAMOTO, Seiji; ARAKI, Yasuyuki; WADA, Takehiko
1J6-12
Invention of Artificial PCR System Towards Development of Functional Artificial Nucleic Acids-2 - Studies on Reactivity of the Oligomer - (IMRAM, Tohoku Univ.) º MURAKAMI, Manami; HAGINIWA, Naomichi; SAKAMOTO, Seiji; ARAKI, Yasuyuki; WADA, Takehiko
1J6-13
Regulation of gene expression by small molecule-inducible ribosomal frameshifting (ISIR, Osaka Univ.) º MATSUMOTO, Saki; MURATA, Asako; HONG, Changfeng; NAKATANI, Kazuhiko
Chair: WADA, Takehiko
(11:20-12:20)
* 11:10-11:20: interval for laptop PC connection.(1J6-15, 1J6-16, 1J6-17, 1J6-18, 1J6-19, 1J6-20)
1J6-15
Searching of the specific binding ligand for CTG repeat sequence (ISIR, Osaka Univ.) º MATSUMOTO, Jun; LI, Jinxing; NAKATANI, Kazuhiko
1J6-16
Design and synthesis of RNA-binding molecules with enthalpy-driven manner (ISIR, Osaka Univ.) º NATSUHARA, Nozomi; DI, Yue; MUKHERJEE, Sanjukta; MURATA, Asako; NAKATANI, Kazuhiko
1J6-17
Synthesis and Properties of Guanidyl Group-containing Oligodiaminogalactose Derivatives Binding to Nucleic Acid Duplexes (Grad. Sch. Frontier Sci., The Univ. of Tokyo; Fac. Pharm. Sci., Tokyo Univ. of Sci.; CREST, JST) º HISADA, Yuki; IWATA, Rintaro; MAEDA, Yusuke; WADA, Takeshi
1J6-18
Construction of double-stranded nucleic acid-intercalator complex for DDS applications (Fac. Eng., Gifu Univ.; Gifu Univ. UGS Drug Discovery and Med. Info. Sci., Gifu Univ.) º KABUMOTO, Marina; IKEDA, Masato; KITADE, Yukio
1J6-19
Evaluation of binding ability of sugar-modified naphthyridine derivatives to DNA and RNA (ISIR, Osaka Univ.) º OKADA, Yasuyuki; AIKAWA, Haruo; NAKATANI, Kazuhiko
1J6-20
Synthesis and evaluation of naphthyridine derivatives with metal-binding moiety (ISIR, Osaka Univ.) º AIKAWA, Haruo; OKADA, Yasuyuki; NAKATANI, Kazuhiko
Thursday, March 26, PM
Chair: KOMIYAMA, Makoto
(13:30-14:30)
* 13:20-13:30: interval for laptop PC connection.(1J6-28, 1J6-29, 1J6-30, 1J6-31, 1J6-32)
1J6-28
Synthesis and Evaluation of the Fluorescent Pyrrole-Imidazole Polyamide Probe Targeting 18 bp in Human Telomeres (Grad. Sch. Sci., Kyoto Univ.; SOKENDAI Dept. of Genet.) º KAWAMOTO, Yusuke; SASAKI, Asuka; HASHIYA, Kaori; IDE, Satoru; BANDO, Toshikazu; MAESHIMA, Kazuhiro; SUGIYAMA, Hiroshi
1J6-29
Developmant of an environmentally sensitive fluorescent 3-deaza-2'-deoxyadenosine derivative and its application to base-discriminating probes (Sch. Eng., Nihon Univ.) º SUZUKI, Azusa; ASO, Tatsuya; SAITO, Isao; SAITO, Yoshio
1J6-30
Synthesis of the thieno[3,4-d]-pyrimidine-based DNA nucleosides as efficient fluorescent probes (Grad. Sch. Sci., Kyoto Univ.) º YAMAMOTO, Seigi; PARK, Soyoung; OKAMURA, Izumi; SUGIYAMA, Hiroshi
1J6-31
Development of novel fluorescence probe using FRET between silylated perylene and nile red (Grad. Sch. Sci. Tech., Gunma Univ.) º NARIYA, Yukino; YAMADA, Keiichi; OKU, Hiroyuki; MORIGUCHI, Tomohisa; SHINOZUKA, Kazuo
1J6-32*
Development of strand-invader by the combination of linear probe and PNA (Grad. Sch. Eng., Nagoya Univ.; EcoTopia Sci. Inst., Nagoya Univ.; PRESTO, JST) NIWA, Rie; AKAHANE, Mariko; KAMIYA, Yukiko; KASHIDA, Hiromu; º ASANUMA, Hiroyuki
Chair: SANDO, Shinsuke
(14:40-15:40)
* 14:30-14:40: interval for laptop PC connection.(1J6-35, 1J6-36, 1J6-38, 1J6-39, 1J6-40)
1J6-35
Construction of the fluorescent sensor with high specificity for the pyrophosphate moiety of ATP (IAE, Kyoto Univ.) º NAKANO, Shun; TAMURA, Tomoki; MORII, Takashi
1J6-36*
Development of the signal-on type of polymerase chain reaction system using cytosine-bulge hairpin probe (ISIR, Osaka Univ.) º TAKEI, Fumie; NAKATANI, Kazuhiko
1J6-38
Thiazole orange-conjugated peptide nucleic acid for fluorescent detection of specific sequences in dsDNA and site-selective photodamage (TARA, Univ. of Tsukuba) º TANAKA, Makiko; SHIGI, Narumi; SUMAOKA, Jun; KOMIYAMA, Makoto
1J6-39
Visible light regulation of gene expression by DNAzyme possessing azobenzene derivatives (Grad. Sch. Eng., Nagoya Univ.) º OOI, Hideaki; TAKAGI, Toshiki; KAMIYA, Yukiko; ASANUMA, Hiroyuki
1J6-40
DNA triple helix specific fluorescence blinking (ISIR, Osaka Univ.; Sch. Biosci. Biotech., Tokyo Tech) º KAWAI, Kiyohiko; MARUYAMA, Atsushi
Chair: NAKATANI, Kazuhiko
(15:50-16:50)
* 15:40-15:50: interval for laptop PC connection.(1J6-42, 1J6-44, 1J6-46, 1J6-47)
1J6-42*
Development of 19F MR probe for DNA detection using Hoechst33258 skeleton (Sch. Mat. Sci., JAIST) º SAKAMOTO, Takashi; HASEGAWA, Daisaku; FUJIMOTO, Kenzo
1J6-44*
19F chemical shift imaging of nucleic acids by ultrafast DNA photocrosslinking (Sch. Mat. Sci., JAIST) º NAKAMURA, Shigetaka; FUJIMOTO, Kenzo
1J6-46
Application of orientation-dependent FRET to the structural analyses of DNA duplex (Grad. Sch. Eng., Nagoya Univ.) º KURIHARA, Ayako; NIWA, Rie; KASHIDA, Hiromu; ASANUMA, Hiroyuki
1J6-47
Self-Assembling Oligonucleotides for Optical Imaging of Hypoxic Regions (Grad. Sch. Eng., Kyoto Univ.) º TAKAGI, Kohei; YOSHIHARA, Kazuki; SON, Aoi; TANABE, Kazuhito
Chair: ASANUMA, Hiroyuki
(17:00-18:00)
* 16:50-17:00: interval for laptop PC connection.(1J6-49, 1J6-51, 1J6-52, 1J6-53, 1J6-54)
1J6-49*
Orthogonal assembly of RuBisCO and Carbonic Anhydrase on a DNA nanoscaffold (IAE, Kyoto Univ.) º DINH, Huyen; NAKATA, Eiji; NGO, Tien Anh; ASHIDA, Hiroki; YOKOTA, Akiho; MORII, Takashi
1J6-51
Construction of organized assembly of proteins in DNA nanotube (IAE, Kyoto Univ.) º NISHIDA, Keisuke; DINH, Huyen; NGO, Anh Tien; NAKATA, Eiji; MORII, Takashi
1J6-52
Construction of perylenediimide assembly using DNA structure as template (Grad. Sch. Eng., Univ. of Hyogo) º IDO, Misa; TAKADA, Tadao; NAKAMURA, Mitsunobu; YAMANA, Kazushige
1J6-53
Construction of porphyrin aggregates through DNA hybridization (Grad. Sch. Eng., Univ. of Hyogo) º IWAKI, Toshihiro; TAKADA, Tadao; NAKAMURA, Mitsunobu; YAMANA, Kazushige
1J6-54
Construction of photoresponsive electrodes functionalized with gold nanoparticles using DNA hybridization (Grad. Sch. Eng., Univ. of Hyogo) º SYUNORI, Kazue; TAKADA, Tadao; NAKAMURA, Mitsunobu; YAMANA, Kazushige
Chair: YAMANA, Kazushige
(18:10-18:40)
* 18:00-18:10: interval for laptop PC connection.(1J6-56, 1J6-57, 1J6-58)
1J6-56
Synthetic molecules for cell-surface functionalization (1): On-cell molecule sensing by functional oligonucleotides (Grad. Sch. Eng., The Univ. of Tokyo) º TSUCHIYA, Akira; HASHIM, Siti Norulhuda; ISE, Shoko; SANDO, Shinsuke
1J6-57
Synthetic molecules for cell-surface functionalization (2) : Exploration of lipid tags that realize efficient anchoring of functional nucleic acid on cell surface (Grad. Sch. Eng., The Univ. of Tokyo) º FURUHATA, Takafumi; KUWAHATA, Kohei; SANDO, Shinsuke
1J6-58
Synthesis and functions of a molecular sensor composed of DNA and lipid molecules (Grad. Sch. Arts and Sci., The Univ. of Tokyo) º SHOHDA, Koh-ichiroh; SUYAMA, Akira
Friday, March 27, AM
Nucleic Acid
Chair: SUGIYAMA, Hiroshi
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(2J6-01, 2J6-03, 2J6-04, 2J6-05, 2J6-06)
2J6-01*
Construction of an enzyme assembly on DNA nanostructure (IAE, Kyoto Univ.) NGO, Anh Tien; º NAKATA, Eiji; SAIMURA, Masayuki; MORII, Takashi
2J6-03
Formation of a covalent linkage of single protein molecule to DNA nanostructure through a DNA binding adaptor (IAE, Kyoto Univ.) º SASAKI, Kenta; NAKATA, Eiji; SAIMURA, Masayuki; MORII, Takashi
2J6-04
Covalent bond formation of a single protein molecule at a defined position on DNA nanoscaffold by using a tag-protein-fused DNA binding adaptor (Institute of Advanced Energy, Kyoto Univ.) º TODA, Takahito; NAKATA, Eiji; SAIMURA, Masayuki; MORII, Takashi
2J6-05
Detection of influenza virus using sialyllactose -modified 3-way junction DNA (Grad. Sch. Human Dev. Env., Kobe Univ.; ISIR, Osaka Univ.) º YAMABE, Miyuki; AKAMATSU, Daichi; EBARA, Yasuhito; KAIHATSU, Kunihiro; KATO, Nobuo
2J6-06
Discovery of transcriptional regulator RNA motifs with specific binding ability to HEXIM1 (KIT) YOSHIMOTO, Asako; º YOSHIMOTO, Kodai; KISHIMOTO, Kyosuke; KOBORI, Akio; MURAKAMI, Akira
Chair: KOBORI, Akio
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(2J6-08, 2J6-09, 2J6-10, 2J6-11, 2J6-13)
2J6-08
Single-molecule observation of interaction of RNA aptamers (Grad. Sch. Sci., Kyoto Univ.) º TAKEUCHI, Yosuke; ENDO, Masayuki; HIDAKA, Kumi; TOULMÉ, Jean-jacques; SUGIYAMA, Hiroshi
2J6-09
Single-molecule mechanochemical sensing using DNA nanostructures (iCeMS, Kyoto Univ.; Univ. of Kent) º ENDO, Masayuki; KOIRALA, Deepak; SHRESTHA, Prakash; MANDAL, Shankar; EMURA, Tomoko; HIDAKA, Kumi; MAO, Hanbin; SUGIYAMA, Hiroshi
2J6-10
Lipid bilayer-supported two-dimensional self-assembly of DNA origami nanostructures (Grad. Sch. Sci., Kyoto Univ.) º SUZUKI, Yuki; ENDO, Masayuki; SUGIYAMA, Hiroshi
2J6-11*
Evaluation of the cluster effect by systematically assembling ATP-binding RNP receptors on DNA origami (IAE, Kyoto Univ.) º ANNONI, Chiara; NAKANO, Shun; YOSHIMURA, Yuki; NAKATA, Eiji; MORII, Takashi
2J6-13
Evaluation of the substrate selectivity of clustered receptors (IAE, Kyoto Univ.) º YOSHIMURA, Yuki; ANNONI, Chiara; NAKANO, Shun; NAKATA, Eiji; MORII, Takashi
Chair: MORI-I, Takashi
(11:20-12:10)
* 11:10-11:20: interval for laptop PC connection.(2J6-15, 2J6-17, 2J6-18, 2J6-19)
2J6-15*
Design and synthesis of novel small-molecule ligand for targeting CUG trinucleotide repeat (ISIR, Osaka Univ.) º LI, Jinxing; MATSUMOTO, Jun; NAKATANI, Kazuhiko
2J6-17
Multiple chemical approaches control cell adhesion (Fac. Med., Univ. of Miyazaki) º LIU, Hongshan; ISHIZUKA, Takumi; XU, Yan
2J6-18
Macrocyclic Polyoxazoles as telomere RNA and DNA G-Quadruplex-binding Ligands (Fac. Med., Univ. of Miyazaki) º LIU, Xiao; ISHIZUKA, Takumi; XIAO, Chaoda; IIDA, Keisuke; NAGASAWA, Kazuo; XU, Yan
2J6-19
19F NMR for probing human telomere RNA G-quadruplex structure (Fac. Med., Univ. of Miyazaki) º BAO, Hongliang; ISHIZUKA, Takumi; XU, Yan
Friday, March 27, PM
Chair: YOSHIDA, Wataru
(14:30-15:30)
* 14:20-14:30: interval for laptop PC connection.(2J6-34, 2J6-35, 2J6-36, 2J6-37, 2J6-39)
2J6-34
Creation of N3-modified thioflavin T analogs targeting G-quadruplex (Grad. Sch. Sci. Tech., Gunma Univ.) º KATAOKA, Yuka; FUJITA, Hiroto; KASAHARA, Yuuya; KUWAHARA, Masayasu
2J6-35
Development of a visual gene detection method with low background using polymerase reactions. (Grad. Sch. Sci. Tech., Gunma Univ.) º FUJITA, Hiroto; KATAOKA, Yuka; KUWAHARA, Masayasu
2J6-36
Synthesis of G-quadruplex ligands by dual interaction strategy and evaluation of their stabilization ability (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º MA, Yue; IIDA, Keisuke; NAGASAWA, Kazuo
2J6-37*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (6) : Binding mechanism of G-quadruplex and its ligands elucidated by pressure effects (FIBER, Konan Univ.) º TAKAHASHI, Shuntaro; SUGIMOTO, Naoki
2J6-39
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (7) : Molecular crowding effect on ribozyme- or protein-based polymerase reactions (FIBER, Konan Univ.) º OKURA, Hiromichi; TAKAHASHI, Shuntaro; SUGIMOTO, Naoki
Chair: TORIGOE, Hidetaka
(15:40-16:40)
* 15:30-15:40: interval for laptop PC connection.(2J6-41, 2J6-42, 2J6-43, 2J6-44, 2J6-45, 2J6-46)
2J6-41
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (12) : A detection system of RNA G-quadruplex with sequence-specificity utilizing thioflavin T (FIRST, Konan Univ.; Grad. Sch. Eng., Nagoya Univ.; FIBER, Konan Univ.) º MAEDA, Ryuichi; MORIMOTO, Kazuhiro; KASHIDA, Hiromu; ASANUMA, Hiroyuki; SUGIMOTO, Naoki; MIYOSHI, Daisuke
2J6-42
Nucleic Acids Chemistry beyond the Watson Crick Double Helix (14) : Development of RNA G-quadruplex specific ligands (FIRST, Konan Univ.) MATSUNO, Hitoshi; SHIMONO, Shu-ji; SUGIMOTO, Naoki; º MIYOSHI, Daisuke
2J6-43
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (8):Importance of interaction between loop regions affecting stabilization of i-motif DNA structure (FIBER, Konan Univ.) º FUJII, Taiga; SUGIMOTO, Naoki
2J6-44
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (9):Development of novel guanine derivative to recognize 8-oxoguanine in G-quadruplex (FIBER, Konan Univ.) º FUJII, Taiga; SUGIMOTO, Naoki
2J6-45
Development of DNA methylation detection system focused on stability of G-quadruplex structure (TUT) º YOSHIOKA, Hitomi; IIDA, Keisuke; NAGASAWA, Kazuo; IKEBUKURO, Kazunori; KARUBE, Isao; YOSHIDA, Wataru
2J6-46
Development of G-quadruplex DNA and RNA Specific-Binding Proteins (Shizuoka University Graduate School of Science) º MIYAWAKI, Arisa; TAKAHAMA, Kentaro; OKUSHIMA, Ayako; OYOSHI, Takanori
Chair: KUWAHARA, Masayasu
(16:50-17:50)
* 16:40-16:50: interval for laptop PC connection.(2J6-48, 2J6-50, 2J6-51, 2J6-53)
2J6-48*
Detection of the prion by the peroxidase activity of hemin-quadruplex RNA complex (Fac. Sci., Tokyo Univ. of Sci.; IAE, Kyoto Univ.) HASHIZUME, Yukiko; MASHIMA, Tsukasa; KATAHIRA, Masato; º TORIGOE, Hidetaka
2J6-50
Synthesis of unsymmetrical macrocyclic hexaoxazole compounds and evaluation of the stabilizing ability of telomeric G-quadruplex (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º SAKUMA, Mai; TSUSHIMA, Yamato; MA, Yue; IIDA, Keisuke; NAGASAWA, Kazuo
2J6-51*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (1): DNA G-quadruplexes control RNA-folding and gene expression (FIBER, Konan Univ.) º TATEISHI, Hisae; ENDOH, Tamaki; SUGIMOTO, Naoki
2J6-53
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (2) : DNA G-triplexes control production of RNA transcript (FIBER, Konan Univ.) º SUBRAMANIYAM, Rajalakshmi; TATEISHI, Hisae; SUGIMOTO, Naoki
Chair: NAGASAWA, Kazuo
(18:00-18:40)
* 17:50-18:00: interval for laptop PC connection.(2J6-55, 2J6-56, 2J6-57, 2J6-58)
2J6-55
Preparation and evaluation of the mismatch binding molecule immobilized Au-SiO2 surface. (ISIR, Osaka Univ.) º MICHIKAWA, Akiko; VERMA, Rajiv Kumar; NAKATANI, Kazuhiko
2J6-56
Synthesis and properties of oligonucleotides containing isophthalic acid derivatives (Grad. Sch. Biosci. Biotech., Tokyo Tech) º KAEWSOMBOON, Tanasak; SHIMOYAMA, Atsushi; YUASA, Hideya; OHKUBO, Akihiro
2J6-57
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (5) : Microscopic analysis of the binding of molecular ions to DNA using molecular dynamics simulation (FIBER, Konan Univ.) º NAKANO, Miki; TATEISHI, Hisae; TANAKA, Shigenori; SUGIMOTO, Naoki
2J6-58
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (13) : Kinetic analysis for adsorption of structured DNA onto graphene oxide (FIRST, Konan Univ.; FIBER, Konan Univ.) º UEDA, Yu-mi; ZOUZUMI, Yu-ki; SUGIMOTO, Naoki; MIYOSHI, Daisuke
Saturday, March 28, AM
Nucleic Acid
Chair: TAKEOKA, Shinji
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(3J6-01, 3J6-02, 3J6-03, 3J6-04, 3J6-05)
3J6-01
Preparation of potassium ion responsive hydrogels using DNA-PEG-DNA triblock copolymers (Fac. Chem. Materials and Bioeng., Kansai Univ.) º TANAKA, Shizuma; FUKUSHIMA, Kazuki; WAKABAYASHI, Kenta; KUZUYA, Akinori; OHYA, Yuichi
3J6-02
A pH-responsive Hydrogel using DNA-PEG-DNA triblock as macromonomers (Fac. Chem. Materials and Bioeng., Kansai Univ.) º FUKUSHIMA, Kazuki; TANAKA, Shizuma; WAKABAYASHI, Kenta; KUZUYA, Akinori; OHYA, Yuichi
3J6-03
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (3) : Regulation of transcription by cyclic naphthalene diimide of G-qaudruplex DNA binding ligand (FIBER, Konan Univ.) º TATEISHI, Hisae; ESAKI, Yugo; SATO, Shinobu; TAKENAKA, Shigeori; SUGIMOTO, Naoki
3J6-04
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (4): Interaction of nucleolin with DNA and RNA G-quadruplexes (FIBER, Konan Univ.) º PRAMANIK, Smritimoy; TATEISHI, Hisae; TAKAHASHI, Shuntaro; NAOKI, Sugimoto
3J6-05*
Effects of conformationally restricted guanosines on G-quadruplex structure (Fac. Med., Univ. of Miyazaki) º ISHIZUKA, Takumi; XU, Yan
Chair: XU, Yan
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(3J6-08, 3J6-10, 3J6-12)
3J6-08*
Identification of nucleic binding specificities of TAF15 (Shizuoka University Graduate School of Sciense) º TAKAHAMA, Kentaro; OKUSHIMA, Ayako; OYOSHI, Takanori
3J6-10*
Development of a small molecule that binds RNA G-quadruplex and its utilization (iCeMS, Kyoto Univ.) º KATSUDA, Yousuke; SATO, Shin-ichi; UESUGI, Motonari
3J6-12*
Live-Cell Imaging of Endogenous mRNAs with a Small Molecule (iCeMS, Kyoto Univ.) º SATO, Shin-ichi; YOUSUKE, Katsuda; MIZUKI, Watanabe; MOTONARI, Uesugi
Chair: KUZUYA, Akinori
(11:20-12:20)
* 11:10-11:20: interval for laptop PC connection.(3J6-15, 3J6-16, 3J6-17, 3J6-19, 3J6-20)
3J6-15
G-quadruplex formation triggered by irradiation of Malachite Green copolymer (Dept. of Chem. Eng., NNCT) NISHIMOTO, Noriko; º UDA, Ryoko
3J6-16
Structural characterization of a complex between heme and G-quadruplex DNA formed from d(TTAGGGT) (Grad. Sch. Pure Appl. Sci., Univ. of Tsukuba) º KINOSHITA, Masashi; SHIMIZU, Haruna; TAI, Hulin; SAITO, Kaori; SHIBATA, Tomokazu; YAMAMOTO, Yasuhiko
3J6-17*
A firmly hybridizable, DNA-like architecture with DAD/ADA and ADD/DAA-type nonnatural base pairs (Grad. Sch. Med. Pharm. Sci. Edu., Univ. of Toyama) º SHIRATO, Wataru; CHIBA, Junya; INOUYE, Masahiko
3J6-19
Enzymatic Ligation of Precisely Designed, C-Nucleoside-based Chimera DNAs by T4 DNA Ligase (Grad. Sch. Pharm. Sci., Univ. of Toyama) º ODA, Yutaro; KUROSAKI, Fumihiro; SHIRATO, Wataru; CHIBA, Junya; INOUYE, Masahiko
3J6-20
Synthesis and evaluation of the reactivity of 7-deaza-6-vinylguanosine derivatives (IMRAM, Tohoku Univ.) º ABE, Yusuke; YAMADA, Ken; NAGATSUGI, Fumi; IDA, Yuta; KUSANO, Shuhei
Saturday, March 28, PM
Chair: INOUYE, Masahiko
(13:30-14:30)
* 13:20-13:30: interval for laptop PC connection.(3J6-28, 3J6-30, 3J6-32)
3J6-28*
Design of a novel acyclic artificial nucleic acid for the stabilization of duplexes with natural nucleic acids (Grad. Sch. Eng., Nagoya Univ.) º MURAYAMA, Keiji; KASHIDA, Hiromu; ASANUMA, Hiroyuki
3J6-30*
Control of the thermal stability of DNA duplexes based on metal complexation of 5-hydroxyuracil nucleobases (Grad. Sch. Sci., The Univ. of Tokyo) º NISHIYAMA, Kotaro; TAKEZAWA, Yusuke; SHIONOYA, Mitsuhiko
3J6-32*
Development of novel pseudo base pair based on charge transfer interaction and its formation of artificial duplex (Grad. Sch. Eng., Nagoya Univ.; Grad. Sch. Eng., Nagoya Univ.) º DOI, Tetsuya; SAKAKIBARA, Takumi; KASHIDA, Hiromu; ASANUMA, Hiroyuki
Chair: SHINOZUKA, Kazuo
(14:40-15:40)
* 14:30-14:40: interval for laptop PC connection.(3J6-35, 3J6-36, 3J6-37, 3J6-39, 3J6-40)
3J6-35
Time-resolved study on duplex formation and dissociation of photoresponsive DNA (Grad. Sch. Sci., Kyoto Univ.) º NAKASONE, Yusuke; OOI, Hideaki; KAMIYA, Yukiko; ASANUMA, Hiroyuki; TERAZIMA, Masahide
3J6-36
Inhibition of gene expression of EGFP mRNA in living cells using photoresponsive α-haloaldehyde derivative-conjugated oligoribonucleotides (KIT) SUGIHARA, Yuta; º NAKATA, Yuki; YAMAYOSHI, Asako; MURAKAMI, Akira; KOBORI, Akio
3J6-37*
Development and photo-cross-linking properties of photoresponsive oligonucleotides having a caged α-haloaldehyde group (KIT) º SUGIHARA, Yuta; NAKATA, Yuki; YAMAYOSHI, Asako; MURAKAMI, Akira; KOBORI, Akio
3J6-39
Locating the uracil-5-yl radical formed in DNA containing 5-bromouracil (Grad. Sch. Sci., Kyoto Univ.) º HASHIYA, Fumitaka; SUGIYAMA, Hiroshi
3J6-40
Stereocontrolled synthesis of dinucleoside phosphorothioates using chiral acids as activators (Fac. Eng., Gifu Univ.) º ORI, Kensuke; OKA, Natsuhisa; ANDO, Kaori
Chair: KOBORI, Akio
(15:50-16:50)
* 15:40-15:50: interval for laptop PC connection.(3J6-42, 3J6-43, 3J6-44, 3J6-45, 3J6-46, 3J6-47)
3J6-42
Synthesis and properties of modified triplex forming oligonucleotides containing thiocarbonyl groups (Grad. Sch. Biosci. Biotech., Tokyo Tech) º MIYAUCHI, Koichiro; SHIMOYAMA, Atsushi; YUASA, Hideya; OHKUBO, Akihiro
3J6-43
Synthesis and properties of a modified DNA containing dithioacetal linkage (Grad. Sch. Sci. Tech., Gunma Univ.) º SEKINE, Mitsuaki; MORIGCHI, Tomohisa; SHINOZUKA, Kazuo
3J6-44
Development of novel modified DNA including deoxyuridine having guanidinium group at the C-5 position (Grad. Sch. Sci. Tech., Gunma Univ.) º HORIGUCHI, Yuka; YAMADA, Keiichi; OKU, Hiroyuki; MORIGUCHI, Tomohisa; SHINOZUKA, Kazuo
3J6-45
Synthesis and evaluation of a 2´-5´ modified branch RNA containing 5´-amino guanosine at the branch point (Sch. Biosci. Biotech., Tokyo Tech; McGill University Department of Chemistry) TAGO, Nobuhiro; º KITAGAWA, Ryo; KATOLIK, Adam; CLARK, Nathaniel; MONTEMAYOR, Eric; HART, P. John; MASAKI, Yoshiaki; KANAMORI, Takashi; SEKINE, Mitsuo; SEIO, Kohji; DAMHA, Masad
3J6-46
Hybridization property and gene regulation by phosphorothioate DNA having C-5 trisamine modified 2’-OMe uridine (Grad. Sch. Sci. Tech., Gunma Univ.) º KOBORI, Seiichiro; OKU, Hiroyuki; YAMADA, Keiichi; MORIGUCHI, Tomohisa; INOUE, Yusuke; SHINOZUKA, Kazuo
3J6-47
Secondary structure formation of amphiphilic DNAs and their binding to the lipid bilayer membrane (ISIR, Osaka Univ.) º YAMAGUCHI, Hayato; MATSUZAKI, Koichi; MAKISHI, Shingo; DOHNO, Chikara; NAKATANI, Kazuhiko
Chair: DOHNO, Chikara
(17:00-17:40)
* 16:50-17:00: interval for laptop PC connection.(3J6-49, 3J6-51, 3J6-52)
3J6-49*
Induction of an Artificial DNA Three-way Junction Structure Triggered by Metal Complexation (Grad. Sch. Sci., The Univ. of Tokyo) º TAKEZAWA, Yusuke; YONEDA, Shuhei; SHIONOYA, Mitsuhiko
3J6-51
Synthesis of nucleosides by Mitsunobu N-glycosidation reactions (Grad. Sch. Biosci. Biotech., Tokyo Tech) TOKUGAWA, Munefumi; º KANEKO, Kazuhei; KANAMORI, Takashi; MASAKI, Yoshiaki; SEKINE, Mitsuo; SEIO, Kohji
3J6-52
Synthesis and properties of 2´-O-[2-(N-methylcarbonyl)ethyl] (MCE) modified 2-thioribothymidine (Grad. Sch. Biosci. Biotech., Tokyo Tech) º YAMAMOTO, Keishi; MASAKI, Yoshiaki; ISHII, Akihiro; INDE, Takeshi; KANAMORI, Takashi; SEIO, Kohji; SEKINE, Mitsuo
Sunday, March 29, AM
Nucleic Acid
Chair: MORI-I, Takashi
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(4J6-01, 4J6-03, 4J6-04, 4J6-05)
4J6-01*
The mechanism of DNA demethylation by Tet protein (Kyoto Univ. Graduate School of Science) º KIZAKI, Seiichiro; SUZUKI, Yuki; CHANDRAN, Anandhakumar; HAN, Yongwoon; ENDO, Masayuki; HARADA, Yoshie; SUGIYAMA, Hiroshi
4J6-03
Methylation analysis in hTERT Gene using Electrochemical hybridization assay (Grad. Sch. Eng., KIT) HARAGUCHI, Kazuya; SAEKI, Toshiro; º SATO, Shinobu; TOMINAGA, Kazuhiro; TAKENAKA, Shigeori
4J6-04
Electrochemical gene detection of ferrocenylnaphthalene diimide carrying .beta.-cyclodextrin coupled with DNA-immobilized electrode (Grad. Sch. Eng., KIT) º YAGAWA, Saori; SATO, Shinobu; TAKENAKA, Shigeori
4J6-05*
Duallozyme: a dually activatable allosteric ribozyme (Grad. Sch. Sci., The Univ. of Tokyo; Grad. Sch. Pharm. Sci., Tohoku Univ.) º KURIYAMA, Mituhiro; NUMAZAKI, Takumi; KONDO, Yoshinori; KATO, Yoshio; TANAKA, Yoshiyuki
Chair: TAKEZAWA, Yusuke
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(4J6-08, 4J6-09, 4J6-10, 4J6-12, 4J6-13)
4J6-08
Development of DNA-based hybrid catalyst by rational creation of an active site. (Grad. Sch. Sci., Kyoto Univ.) º OKAMURA, Izumi; PARK, Soyoung; SUGIYAMA, Hiroshi
4J6-09
Investigation of DNA metalloenzymes for asymmetric Diels-Alder reaction (Grad. Sch. Sci., Kyoto Univ.) º PARK, Soyoung; OKAMURA, Izumi; SUGIYAMA, Hiroshi
4J6-10*
Screening of ribonucleopeptide libraries with catalytic groups (IAE, Kyoto Univ.) º TAMURA, Tomoki; ARIYAMA, Kenta; NAKANO, Shun; MORII, Takashi
4J6-12
Evaluation of an ester hydrolysis activity of ribonucleopeptide with a zinc(II) complex (IAE, Kyoto Univ.) º ARIYAMA, Kenta; TAMURA, Tomoki; NAKANO, Shun; MORII, Takashi
4J6-13
Stimuli-responsive DNA splicing through global conformational change (Grad. Sch. Sci. Technol., Kumamoto Univ.; CREST, JST) º IHARA, Toshihiro; OHURA, Hiroyuki; KODANI, Hidenaga; URATA, Shoma; KITAMURA, Yusuke
Chair: IHARA, Toshihiro
(11:20-11:40)
* 11:10-11:20: interval for laptop PC connection.(4J6-15, 4J6-16)
4J6-15
Synthesis and properties of 3'-O-protected nucleoside 5'-triphosphate derivatives (Sch. Biosci. Biotech., Tokyo Tech) º TANAKA, Hirotomo; SHIMOYAMA, Atsushi; YUASA, Hideya; OHKUBO, Akihiro
4J6-16
Reduction-activatable protecting groups for the synthesis of pro-oligonucleotides (Fac. Eng., Kanagawa Univ.) º SANEYOSHI, Hisao; IKETANI, Koichi; KONDO, Kazuhiko; HIYOSHI, Yuki; OKAMOTO, Itaru; ONO, Akira